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Transformative Potential of MXenes in Healthcare: Opportunities and Challenges for Diagnostics and Therapeutics

MXenes in Healthcare

We are pleased to announce the publication of our latest review article on MXenes in Healthcare. This work provides a comprehensive overview of the emerging role of MXenes—an advanced class of two-dimensional (2D) materials—in transforming medical diagnostics and therapeutics.

The review highlights MXenes’ remarkable properties, including high electrical conductivity, tunable surface chemistry, and large surface area, which make them strong candidates for applications in drug delivery, biosensing, tissue engineering, and cancer therapy. At the same time, it addresses key challenges that must be overcome for successful clinical translation: limited physiological stability, potential cytotoxicity, oxidative degradation, synthesis scalability, environmental sustainability, and regulatory approval pathways.

The article also discusses promising strategies to enhance MXene performance, such as surface functionalization, composite formation with other 2D materials, green synthesis approaches, targeted drug delivery, and standardized biocompatibility testing. These insights provide practical guidelines for engineering MXenes into safe and effective biomedical technologies.

This review serves as both a summary of current progress and a roadmap for future research, aiming to facilitate the integration of MXenes into personalized and regenerative medicine.

Authors: Keshav Narayan Alagarsamy, Leena Regi Saleth, Kateryna Diedkova, Veronika Zahorodna, Oleksiy Gogotsi, Maksym Pogorielov, and Sanjiv Dhingra.